[...The smile Milla gets is softer, kinder than Sayaka's usual.]

Thank you...I appreciate that.

[Still, once that's out of the way--]

It depends on the country, but yes! I think...well, have you heard anyone using Mr. or Ms. or the like before? It's sort of like that--an indicator of how familiar you are with the person you're speaking to. There's different ones for superiors and the like too.